Join us on 12-15-2022 for a live seminar about RNA SEQ
We offer our platforms and services to the entire drug discovery community and are committed to doing whatever it takes to find you the best therapeutics. Our commitment to reinvesting 100% of our revenue into innovation means we are always acquiring and developing new groundbreaking technologies to make you more successful.
We offer foundational biologics discovery technologies through bespoke campaigns or through licensing into your labs. Our commitment to reinvesting 100% of our revenue into innovation means we are always developing new groundbreaking platforms and protocols to make our collaborators more successful.
Academic scientists
Small and medium biotech
Large biopharma
We offer an ever-growing stable of services and cutting-edge technology platforms to help you discover the best therapeutic antibodies in the ideal formats for your therapeutic targets. Discover with us in our lab or by licensing our platforms for use in yours.
We pair Alloy’s foundational, world-class antibody discovery expertise with the pioneering minds behind soluble T cell receptor (TCR) therapeutics to discover novel immunotherapies for our partners. Run bespoke discovery campaigns with Keyway™ TCR Discovery.
We offer foundational technologies and discovery capabilities that address the therapeutic index and delivery challenges that have historically limited the promise of antisense oligonucleotide (ASO) drug candidates. Collaborate with us to transform your existing sequences or discover de novo molecules in our proprietary AntiClastic™ ASO format, which has improved ASO potency by as much as 25X.
We expanded from antibodies into adjacent biologic modalities to help our partners find the best therapeutic for the disease, regardless of format. We just launched our newest modality, genetic medicines, and have active R&D projects in cell therapies, peptides, and delivery.
Click each icon below to learn more about our work in each area.
We are a team of 100+ people across 5 research sites, and our work is amplified by our ecosystem of hundreds of companies and thousands of engaged researchers.
Our venture studio 82VS activates Alloy’s platforms, discovery services groups, and company creation expertise to help brilliant scientific entrepreneurs efficiently advance new medicines pipelines.
There is no one-size-fits-all engagement with Alloy. We partner flexibly and creatively across each collaboration, activating our stable of platform technologies, discovery services, and company creation capabilities to meet our partners’ goals.
We collaborate with our partners to leverage the full potential of our technology and services, acting as an innovation engine for the drug discovery industry. How can we help you in your quest to fight disease?
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Our research facilities:
Boston, MA
Cambridge, UK
Basel, CH
Athens, GA
© 2023 Alloy Therapeutics, Inc. All Rights Reserved.
Thanks for your interest in our white paper, Targeting GPCRs with DeepImmune Antibody Discovery.
G protein-coupled receptors (GPCRs) play a central role in multiple physiological functions, from endocrine sensing to neurotransmission to chemotaxis of immune cells. This class has long been an attractive target for novel antibody drug discovery campaigns in multiple disease indications, but their unique nature produces many challenges for in vivo antibody discovery. In this white paper, we detail how our humanized mouse discovery platform, the ATX-Gx™, have been successfully utilized for GPCR-targeted antibody discovery, Alloy Antibody Discovery’s DeepImmune™ module builds on this robust in vivo discovery platform, coupling best-in-class immunogen production with multiple binder recovery approaches, and advanced machine-learning-based techniques for lead identification and optimization.
I’d like more material about Keyway TCR Discovery
Thanks for your interest in our recent Keyway TCRm Discovery webinar, Increasing Target Specificity and Tackling Intracellular Targets for TCRm Therapeutics Development with Keyway’s TCRm Discovery Offering. In it, the team at the helm of our TCR mimic discovery campaigns shared:
1. An overview of common challenges to intracellular protein-targeting drug discovery
2. Keyway’s industry-leading solutions to TCRm/TCR-based therapeutic discovery including its proprietary specificity screening and high-quality pMHC complex antigen production capabilities
3. A case study featuring the discovery of a panel of highly specific, functional TCRm binders against an intracellular immuno-oncology target
Upon filling out this form, you will receive an email with a link to the webinar recording.