Antibodies and Bispecifics
Platforms and services accelerating discovery of innovative antibody therapeutics
- Explore Antibodies & Bispecifics
Antibody Platforms
Unmatched transgenic models for human antibody discovery
Our world-class, fully human in vivo discovery platforms are designed to provide exceptional strain diversity including hyperimmune mice for challenging targets and common light-chain (CLC) strains for bispecific development. Through our ATX-GX™ license, we offer broad access to the platform with flexible business terms enabling our partners to make life-changing medicines.
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Monoclonal Discovery
Your ideal antibody powered by proprietary technologies
At Alloy, we combine cutting-edge technology with a personalized approach to antibody discovery, backed by over 100 years of collective expertise and tailored to meet your specific needs. We leverage our proprietary humanized transgenic mice combined with an advanced suite of technologies including:
- Optimized immunization & B cell enrichment strategies
- AI/ML powered clone selection
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Robust testing for binding, developability, and function.
Bispecific Discovery
The world’s most advanced bispecific discovery service
We overcome the traditional complexity and developability challenges for bispecific discovery by providing a fully integrated workflow from drug concept to bispecific lead including antibody discovery, bispecific format engineering, and functional screening.
Optimization
Antibody optimization services to hit your target product profile
We offer advanced antibody optimization workflows and strategies to ensure that your drug candidates are fine-tuned for clinical success. By applying cutting-edge tools, we can unlock the full potential of your antibody program.
AI/ML Powered In Silico Design
From optimizing binding affinity and stability to reducing immunogenicity and improving developability, our sophisticated computational tools enable the design of next generation antibodies with precision and speed.
high-throughput expression and testing
Maximize efficiency and achieve breakthrough results by rapidly expressing and testing hundreds to thousands of variants for binding, stability, and functionality.
Advanced display platforms & technologies
We combine AI/ML designed libraries with cutting-edge display platforms to rapidly select leads with improved affinity, specificity, and developability.
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