Platforms and services accelerating discovery of innovative antibody therapeutics

Antibody DISCOVERY Platforms

Unmatched transgenic models for human antibody discovery

Our world-class, fully human in vivo discovery platforms are designed to provide exceptional strain diversity including hyperimmune mice for challenging targets and common light-chain (CLC) strains for multispecific development, with proprietary technologies that deliver high-quality, differentiated antibodies. Through our ATX-GX™ license, we offer broad access to the platform with flexible business terms enabling our partners to make life-changing medicines. 

Partners

200+

and growing

110+

Active drug programs
declared by partners
INDs filed

25+v

by partners since first platform
ANTIBODY DISCOVERY SERVICES

Your ideal antibody powered by proprietary technologies

At Alloy, we combine cutting-edge technologies with a personalized approach to antibody discovery services, backed by over 100 years of collective expertise and tailored to meet your specific needs. We de-risk your candidates at every stage using our proprietary humanized transgenic mice and integrated technology workflows, including: 

MULTISPECIFIC ENGINEERING

Utilizing advanced capabilities

We simplify multispecific antibody discovery through an integrated platform that spans antibody discovery, engineering, and screening, helping advance high-quality therapeutic leads with greater speed and confidence.

Optimization

Antibody optimization services to hit your target product profile

We offer advanced antibody optimization workflows and strategies to ensure that your drug candidates are fine-tuned for clinical success. By applying cutting-edge tools, we rapidly engineer your lead candidates for affinity, specificity, or developability to unlock the full potential of your antibody program.

AI/ML Powered In Silico Design

From optimizing binding affinity and stability to reducing immunogenicity and improving developability, our sophisticated computational tools enables the design of next generation antibodies with precision and speed.

high-throughput expression and testing

Maximize efficiency and achieve breakthrough results by rapidly expressing and testing hundreds to thousands of variants for binding, stability, and functionality.

Advanced display platforms and technologies

We combine AI/ML designed libraries with cutting edge display platforms to rapidly select leads with improved affinity, specificity, and developability.