Webinar Registration: Beyond Affinity

Optimize for more than affinity: Multi-Parameter Optimization of Multispecific Building Blocks

Webinar Overview

A promising antibody building block may have the affinity you want while carrying potential developability liabilities that limit its potential in a multispecific format. Addressing those liabilities without compromising the properties that made the molecule valuable requires optimization across multiple parameters.

Join Alloy scientist Dalton Makrush to explore a rapid, multi-parameter approach that integrates in vitro and in silico workflows to evaluate and optimize developability alongside affinity.

In this webinar, you will learn how Alloy:

  • Evaluates developability alongside affinity in multispecific building blocks
  • Integrates in vitro and in silico workflows for rapid, multi-parameter optimization
  • Improves limiting properties while monitoring favorable starting characteristics
  • Applies these approaches in practice through representative case studies

Meet the speaker

Dalton Makrush

Senior Scientist, Global Bioanalytics

Dalton Markrush, Senior Scientist of Bioanalytics at Alloy Therapeutics, develops methods and workflows to accelerate early- and late-stage antibody developability for partner programs. Prior to joining Alloy, Dalton worked on protein analytics and binding at Compass Therapeutics. He holds a Master’s degree in Biotechnology from Northeastern University.

Register for the webinar

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Last updated: August 28, 2026